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Porcine pluripotent stem cells: progress, challenges and prospects
Jianyong HAN, Yi-Liang MIAO, Jinlian HUA, Yan LI, Xue ZHANG, Jilong ZHOU, Na LI, Ying ZHANG, Jinying ZHANG, Zhonghua LIU
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1, Pages 8-27 doi: 10.15302/J-FASE-2018233
Pluripotent stem cells (PSCs) are characterized by their capacity for high self-renewal and multipledifferentiation potential and include embryonic stem cells, embryonic germ cells and induced PSCs.
Keywords: embryonic germ cells embryonic stem cells induced pluripotent stem cells pigs pluripotent stem cells
Reprogramming of the pig primordial germ cells into pluripotent stem cells: a brief review
Qijing LEI, Qin PAN, Shuai YU, Na LI, Shulin CHEN, Kuldip SIDHU, Jinlian HUA
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1, Pages 28-32 doi: 10.15302/J-FASE-2018222
Primordial germ cells (PGCs) are regarded as unipotent cells that can produce only either spermatogoniaHowever, PGCs can be converted into the pluripotent state by first dedifferentiation to embryonic germcells and then by reprogramming to induce them to become pluripotent stem cells (iPSCs).These two stages can be completely implemented with mouse cells.
Keywords: pig pluripotent stem cells primordial germ cells reprogramming
The past, present and future of bovine pluripotent stem cells: a brief overview
Xiuchun TIAN
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1, Pages 3-7 doi: 10.15302/J-FASE-2018247
Although the pursuit of bovine embryonic stem cells started more than 26 years ago for the purposeof gene-targeting, true pluripotent stem cells in this economically important species are still elusiveWith the rapid advances in genome-editing and cloning using homologously recombined somatic cells, theneed for pluripotent stem cells for precise genetic modification in any species became questionable.pluripotency circuitry across mammalian species may be the main objective for studying pluripotent stem cells
Keywords: bovine embryonic induced pluripotent stem cells
Transcriptomics and proteomics in stem cell research
Hai Wang,Qian Zhang,Xiangdong Fang
Frontiers of Medicine 2014, Volume 8, Issue 4, Pages 433-444 doi: 10.1007/s11684-014-0336-0
Stem cells are capable of self-renewal and differentiation, and the processes regulating these eventsparticular, the molecular mechanisms of the self-renewal, proliferation, and differentiation of stem cellsWe reviewed the available information on stem cells by examining published results using transcriptomicmethod will strengthen the study on stem cell biology and promote the clinical applications of stem cells
Keywords: embryonic stem cells transcriptomics proteomics
Progress, problems and prospects of porcine pluripotent stem cells
Hanning WANG,Yangli PEI,Ning LI,Jianyong HAN
Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 1, Pages 6-15 doi: 10.15302/J-FASE-2014009
Keywords: induced pluripotent stem cells embryonic stem cells pig reprogramming
Regulation and function of histone acetyltransferase MOF
Yang Yang, Xiaofei Han, Jingyun Guan, Xiangzhi Li
Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 79-83 doi: 10.1007/s11684-014-0314-6
Keywords: MOF histone acetyltransferase DNA damage repair tumorigenesis embryonic stem cells
Effects of DNA damage on oocyte meiotic maturation and early embryonic development
Shen YIN,Junyu MA,Wei SHEN
Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3, Pages 185-190 doi: 10.15302/J-FASE-2014035
Keywords: DNA damage double-strand breaks (DSBs) oocyte embryo
Factors affecting early embryonic development in cattle: relevance for bovine cloning
Yanna DANG, Kun ZHANG
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1, Pages 33-41 doi: 10.15302/J-FASE-2018228
Female infertility represents a major challenge for improving the production efficiency in the dairy industry. Historically, fertility has declined whereas milk yield has increased tremendously due to intensive genetic selection. evidence reveals about 60% pregnancy loss takes place during the first month following fertilization. Meanwhile, early embryo development is significant for somatic cell nuclear transfer in cattle as a large proportion of cloned embryos fail to develop beyond peri-implantation stage. Oocyte quality is of utmost importance for the early embryo to develop to term for both fertilized and cloned embryos. Epigenetic reprogramming is a key process occurring after fertilization and critical roles of epigenetic modifiers during preimplantation development are now clear. Incomplete epigenetic reprogramming is believed to be a major limitation to cloning efficiency. Treatment of cloned embryos with epigenetic modifying drugs (e.g., Trichostatin A) could greatly improve cloning efficiency in both mice and cattle. Recently, the rapid progress in high-throughput sequencing technologies has enabled detailed deciphering of the molecular mechanisms underlying these events. The robust efficiency of genomic editing tools also presents an alternative approach to the functional annotation of genes critical to early development.
Keywords: bovine cloning embryo development somatic cell nuclear transfer X-inactive specific transcript
Frontiers of Medicine Pages 939-956 doi: 10.1007/s11684-023-0987-9
Keywords: mononuclear diploid cardiomyocytes cell–cell communication cardiac fibroblast single-cell RNA sequencing cardiac regeneration
Rivera, Berenice Miranda-Alcántara, Germán Orozco, Carlos Ponce de León, Luis F. Arenas
Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2, Pages 399-409 doi: 10.1007/s11705-020-1934-9
Keywords: CFD simulation porous media porous electrode pressure drop redox flow battery
Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts
Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,
Frontiers of Medicine 2009, Volume 3, Issue 4, Pages 379-383 doi: 10.1007/s11684-009-0073-y
Keywords: p38 regulated/activated protein kinase gene knockout cell cycle cell proliferation
Determination of telomerase activity in stem cells and non-stem cells of breast cancer
LI Zhi, HE Yanli, ZHANG Jiahua, ZHANG Jinghui, HUANG Tao
Frontiers of Medicine 2007, Volume 1, Issue 3, Pages 294-298 doi: 10.1007/s11684-007-0056-9
Innate and adaptive T cells in influenza disease
Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska
Frontiers of Medicine 2018, Volume 12, Issue 1, Pages 34-47 doi: 10.1007/s11684-017-0606-8
Keywords: influenza innate T cells CD4+ and CD8+ T cells vaccination
4-1BBL expressed by eukaryotic cells activates immune cells and suppresses the progression of murine
Hui QIU, Hui ZHANG, Zuohua FENG
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 20-25 doi: 10.1007/s11684-009-0006-9
Keywords: 4-1BB ligand tumor immunotherapy tumor microenvironment
Comparison of human nasal epithelial cells grown as explant outgrowth cultures or dissociated tissue
Jian Jiao, Na Meng, Hong Wang, Luo Zhang
Frontiers of Medicine 2013, Volume 7, Issue 4, Pages 486-491 doi: 10.1007/s11684-013-0287-x
Keywords: ciliated cells ciliary beat frequency dissociated tissue culture explant culture nasal epithelial cells
Title Author Date Type Operation
Porcine pluripotent stem cells: progress, challenges and prospects
Jianyong HAN, Yi-Liang MIAO, Jinlian HUA, Yan LI, Xue ZHANG, Jilong ZHOU, Na LI, Ying ZHANG, Jinying ZHANG, Zhonghua LIU
Journal Article
Reprogramming of the pig primordial germ cells into pluripotent stem cells: a brief review
Qijing LEI, Qin PAN, Shuai YU, Na LI, Shulin CHEN, Kuldip SIDHU, Jinlian HUA
Journal Article
The past, present and future of bovine pluripotent stem cells: a brief overview
Xiuchun TIAN
Journal Article
Transcriptomics and proteomics in stem cell research
Hai Wang,Qian Zhang,Xiangdong Fang
Journal Article
Progress, problems and prospects of porcine pluripotent stem cells
Hanning WANG,Yangli PEI,Ning LI,Jianyong HAN
Journal Article
Regulation and function of histone acetyltransferase MOF
Yang Yang, Xiaofei Han, Jingyun Guan, Xiangzhi Li
Journal Article
Effects of DNA damage on oocyte meiotic maturation and early embryonic development
Shen YIN,Junyu MA,Wei SHEN
Journal Article
Factors affecting early embryonic development in cattle: relevance for bovine cloning
Yanna DANG, Kun ZHANG
Journal Article
Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in embryonic
Journal Article
Pressure drop analysis on the positive half-cell of a cerium redox flow battery using computational fluid dynamics: Mathematical and modelling aspects of porous media
Rivera, Berenice Miranda-Alcántara, Germán Orozco, Carlos Ponce de León, Luis F. Arenas
Journal Article
Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts
Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,
Journal Article
Determination of telomerase activity in stem cells and non-stem cells of breast cancer
LI Zhi, HE Yanli, ZHANG Jiahua, ZHANG Jinghui, HUANG Tao
Journal Article
Innate and adaptive T cells in influenza disease
Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska
Journal Article
4-1BBL expressed by eukaryotic cells activates immune cells and suppresses the progression of murine
Hui QIU, Hui ZHANG, Zuohua FENG
Journal Article